Based on Madison Avenue in New York City, Helwaser Gallery specializes in post-war and contemporary art, featuring seminal artists such as Alexander Calder, Helen Frankenthaler, Adolph Gottlieb, and Yayoi Kusama. In 1986, the gallery was founded in Paris and initiated significant exhibitions, including a retrospective on Jean Dubuffet (1996), and others on French cubist masters, notably George Braque, Jean Metzinger, and Pablo Picasso. In 2008, Helwaser Gallery marked its inaugural relocation to New York with the group exhibition Red, exhibiting Hans Hofmann, Andy Warhol, and Jean-Michel Basquiat amongst others. Helwaser Gallery reopened its new space in 2019 with a public exhibition program, presenting contemporary artists Anton Ginzburg, Christina Kruse, Boedi Widjaja, and Lin Yan.

Helwaser Gallery has participated in the following art fairs: The Armory Show, Art Miami, Palm Beach Art Fair, Southampton art fair, The Salon Art Design, Paris Art Design, and Brafa (Brussels)